All PPIs present on AtPIN was first classified according to their detection evidence. This classification comprehends direct and indirect evidence as follow:
DIRECT EVIDENCE: This means that the indicated PPI was experimentally demonstrated using Arabidopsis thaliana proteins as model of study. The experiment indicated links to the publication of which this interaction was annotated from.
INDIRECT EVIDENCE: The indicated PPI was proposed based on ortholgs studies. The experiment indicated links to the publication of the orthologous PPI was annotated from.
The second PPI classification is based on how the interaction was demonstrated (direct or indirect methods), the protein cellular compartment location based on data available at SUBA and how this subcellular location was proposed (experimental or predicted).
|PPI detection||Same compartment?||Subcellular location indication|
|Class A||Direct evidence||YES||Experimental|
|Class B||Direct evidence||NO||Experimental|
|Class C||Indirect evidence||YES||Experimental|
|Class D||Direct evidence||YES||Predicted|
|Unkown||Direct / Indirect||No data available||No data available|